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Enzyme Research 是一家拥有超过25年的酶研究的实验室，生产和开发多种用于基本凝血研究的多种酶和辅因子。在过去的十年Enzyme Research Laboratories为科学家参与止血和血栓形成的研究提供了宝贵支持。Enzyme Research通过不断追求产品的zui高品质，赢得了世界各地凝血研究实验室的信任。

Human Kallikrein

HPKa 1303             Human Kallikrein

Activation of Prekallikrein with Factor α-XIIa produces the enzymatically active Kallikrein. Kallikrein is a serine protease which consists of a heavy chain （Mr 52kD） and light chains （Mr either 36 or 33 kD） linked by disulfide bridges. Kallikrein possesses enzymatic activity toward Factor XII, HK, Plasminogen, Factors XI, IX, and VII, prorenin and the complement system. After activation, the activating enzyme Factor XIIa is removed by affinity chromatography. Human Kallikrein purity is determined by SDS-PAGE and shows complete reduction upon incubation with 2-mercaptoethanol.

Buffer composition = 4 mM Sodium Acetate-HCl/0.15 M NaCl/pH 5.3
*Extinction Coefficient （1%） = 11.7
Molecular Weight = ~86,000 daltons