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名称 | [Lys(Ac)382]-p53 (361-393), biotin labeled |
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别名 | [Lys(Ac)382]-p53 (361-393), biotin labeled |
纯度 | 80%,90%,95%,98%,99% |
重量 | 1mg,5mg,10mg,50mg,100mg,1g |
序列(单字母缩写) | Biotin-C6-GSRAHSSHLKSKKGQSTSRHK-K(Ac)-LMFKTEGPDSD-NH2 |
序列(三字母缩写) | Biotin-C6-Gly-Ser-Arg-Ala-His-Ser-Ser-His-Leu-Lys-Ser-Lys-Lys-Gly-Gln-Ser-Thr-Ser-Arg-His-Lys-Lys(Ac)-Leu-Met-Phe-Lys-Thr-Glu-Gly-Pro-Asp-Ser-Asp-NH2?(trifluoroacetate salt) |
基本描述 | This peptide is tumor suppressor protein p53 (368-393). There is a biotinylated lysine follwed by a GG linker at the N-terminal and is acetylated at lysine 382. p53 is an ideal tumor suppressor gene because of its ability to control cell proliferation, and senescence. In response to cell stress, cell damage, or ectopic oncogene, p53 also mediates apoptosis. |
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分子量 | 4034.7 |
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存储条件 | Store at -20°C. Keep tightly closed. Store in a cool dry place. |
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Reference | Kubbutat, M. et al. Lett Nature 387, 299 (1997) Li, M. et al. J Biol Chem 277, 50607 (2002) |
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