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名称 | PAR-4 (1-6)) amide |Protease Activated Receptor-4 (1-6) amide, mouse |
编码 | [245443-52-1] |
别名 | PAR-4 (1-6)) amide |Protease Activated Receptor-4 (1-6) amide, mouse |
纯度 | 80%,90%,95%,98%,99% |
重量 | 1mg,5mg,10mg,50mg,100mg,1g |
序列(单字母缩写) | GYPGKF-NH2 |
序列(三字母缩写) | H-Gly-Tyr-Pro-Gly-Lys-Phe-NH2?(trifluoroacetate salt) |
基本描述 | This peptide based on the proteolytically-revealed tethered ligand sequence of the murine proteinase-activated receptor-4 (PAR-4) was shown to cause platelet aggregation with an EC50 value of about 15 碌M. PAR-4 agonist peptide stimulates thromboxane production by human platelets with the maximal response to this agonist being approximately half of that observed after maximal thrombin stimulation. |
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分子量 | 666.78 |
化学式 | C33H46N8O7 |
存储条件 | Store at -20°C. Keep tightly closed. Store in a cool dry place. |
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Reference | N.Vergnolle, J. Immunol., 163, 5064 (1999) M.D.Hollenberg and M.Saifeddine, Can. J. Physiol. Pharmacol., 79, 439 (2001) Fang, J. et al. Blood 106, 2671(2005) Mulè, F. et al. Gut. 53, 229 (2004) Sekiguchi, F. et al. Drug Design Rev. 1, 287 (2004) Faruqi, T. et al. J. Biol. Chem. 275, 19728 (2000) Greenberg, D. Biochem. 42, 2702 (2003) |
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