listlabs 177B说明书
list biological laboratories公司是世界的科研毒素试剂供应商,其毒素包括霍乱病毒,蛇毒,百日咳毒素等各类毒素,我公司常年低价供应,货期快.有意者请. 百日咳毒素长期现货供应,货号181及180。
listlabs 177B说明书
炭疽毒素Anthrax Toxins
炭疽杆菌是炭疽病的病原体。炭疽杆菌产生的主要毒力因子是γ连接的聚-D-谷氨酸胶囊和由三种成分组成的外毒素,保护性抗原(PA),致死因子(LF)和水肿因子(EF)。这些蛋白质不是单*毒的,而是以二元组合起作用。PA(细胞结合成分)与LF(酶部分之一)的复合物被称为“致死毒素”并可导致死亡。PA和酶促EF一起引起皮肤水肿。分泌后,PA被膜肽酶切割,使63kDa羧基末端片段寡聚化成七聚体。切割是暴露EF和LF的结合位点的必要步骤。组装的PA复合物和相关的LF或EF通过胞吞作用进入细胞。PA介导LF和EF向细胞质的转移,其中这些酶识别并蛋白水解其靶标。LF组分是一种锌依赖性金属蛋白酶,可裂解丝裂原活化蛋白激酶激酶(MAPKK),从而削弱其功能,从而阻断MAPK信号通路。EF是钙调蛋白依赖性腺苷酸环化酶,其在细胞中产生过量的环AMP,导致水肿。目前的研究集中于开发有效的疫苗以及筛选LF酶活性的有效抑制剂。
含有炭疽LF切割位点的FRET肽底物可作为MAPKKide®获得,并可用于评估LF的酶活性。
炭疽毒素
(炭疽保护性抗原和衍生物)
炭疽保护性抗原片段(PA 20)
从炭疽芽孢杆菌
炭疽毒素
(炭疽保护性抗原和衍生物)
保护性抗原(PA)是炭疽毒素的受体结合成分。原始的83kDa蛋白质被细胞弗林蛋白酶样蛋白酶切割,形成活化的63kDa单体PA63。在这种形式中,PA63与其他PA63分子结合形成环状七聚体。PA63还具有对于与细胞表面上形成的孔相邻的酶LF和EF特异性的结合位点,用于易位。对于醉酒细胞,PA应与EF或LF一起使用约7倍过量。
List Labs提供三种不同大小的PA,产品#171是未切割的83kDa蛋白质,产品#174和175是PA63,它们已被激活和纯化,PA63分别与FITC缀合。另外,我们提供从PA,PA20,产品#177切割的约20kDA片段
#177A(50 ug) – $ 340.00
#177B(0.25毫克) – $ 610.00
货号 |
品名 |
规格 |
价格 |
list104 |
Cholera Toxin B Subunit (Choleragenoid) in low salt1 |
0.5mg |
4930 |
list106 |
Cholera Toxin B Subunit Fluorescein Isothiocyanate Conjugate (BFITC) |
0.2mg |
9775 |
list112 |
Cholera Toxin B Subunit Biotin |
0.2mg |
9775 |
list122 |
Enterotoxin Type B from Staphylococcus aureus1,3 |
0.5mg |
7225 |
list123 |
Enterotoxin Type B Toxoid from Staphylococcus aureus 1,3 |
0.25mg |
8075 |
list139 |
Botulinum Neurotoxin Type B Toxoid |
10µg |
6800 |
list150 |
Diphtheria Toxin, unnicked from Corynebacterium diphtheriae |
1mg |
11050 |
list151 |
Diphtheria Toxoid, from Corynebacterium diphtheriae |
0.5mg |
10625 |
list153 |
Toxin A Toxoid from Clostridium difficile |
100µg |
11900 |
list156 |
Pasteurella Multocida Toxin |
50µg |
8075 |
list160 |
Exotoxin A from Pseudomonas aeruginosa |
1mg |
4420 |
list161 |
Shiga Toxin 1 from Escherichia coli1,4,8 |
10µg |
11900 |
list162 |
Shiga Toxin 2 from Escherichia coli1,4,8 |
10µg |
11050 |
list174 |
Anthrax Protective Antigen, Activated (PA 63) from Bacillus anthracis |
0.5mg |
9350 |
list175 |
Anthrax PA 63 – Fluorescein Isothiocyanate Conjugate (PAFITC) |
50µg |
7225 |
list180 |
Pertussis Toxin Islet-Activating Protein Lyophilized in buffer |
50µg |
5525 |
list181 |
Pertussis Toxin Islet Activating Protein Lyophilized (Salt-Free) |
50µg |
5525 |
list184 |
Pertussis Toxin Mutant |
50µg |
5525 |
list186 |
FIMBRIAE 2/3 from B. pertussis |
50µg |
5950 |
list187 |
Pertactin from Bordetella pertussus (69 kDa Protein) |
50µg |
4590 |
list193 |
Tetanus Toxin C Fragment |
10µg |
9350 |
list201 |
LPS from Escherichia coli O111:B4 |
5mg |
3230 |
list206 |
LPS, Escherichia coli 0157:H7 |
10.0mg |
4760 |
list225 |
LPS from Salmonella typhimurium |
5mg |
2890 |
list301 |
LPS from Escherichia coli J5 (Rc) |
5mg |
2890 |
list302 |
LPS from Escherichia coli K12, D31m4 (Re) |
5mg |
2890 |
list304 |
LPS from Salmonella minnesota R595 (Re) |
5mg |
2890 |
list314 |
LPS from Escherichia coli K12 strain LCD25 |
1mg |
2890 |
list400 |
HPT™ LPS, highly purified from Bordetella Pertussis 165 |
1mg |
5100 |
list401 |
Lipid A monophosphoryl from Salmonella minnesota R595 |
1mg |
3400 |
list421 |
Ultra Pure LPS from Escherichia coli O111:B4 |
1mg |
3570 |
list423 |
Ultra Pure LPS from Escherichia coli O55:B5 |
1mg |
3570 |
list433 |
LISTÔ HPTÔ, LPS, highly purified Escherichia coli O113 LPS |
1mg |
4080 |
list434 |
Ultra Pure LPS from Salmonella minnesota R595 (Re) |
1mg |
3400 |
list520 |
SNAPtide® Peptide Substrate (o-Abz/Dnp) (U.S. Patent #6,504,006) |
200nmoles |
9775 |
list521 |
SNAPtide® Peptide Substrate (FITC/DABCYL) (U.S. Patent #6,504,006) |
200nmoles |
8500 |
list523 |
SNAPtideÒ Peptide Substrate flP6 (DABCYL/5-IAF), U.S. Patent Pending #61/252,675 |
200nmoles |
8500 |
list525 |
Control Peptide for SNAPtideÒ #520 |
200nmoles |
8500 |
list526 |
Control Peptide for SNAPtide® #521 |
200nmoles |
8500 |
list528 |
Unquenched Calibration Peptide for SNAPtide® 521 |
50nmoles |
2890 |
list529 |
Unquenched Calibration Peptide for SNAPtide® 520 |
50nmoles |
2890 |
list530 |
MAPKKide® Peptide Substrate (o-Abz/Dnp) |
200nmoles |
5100 |
list531 |
MAPKKide® Peptide Substrate (DABCYL/FITC) |
200nmoles |
5100 |
list532 |
MAPKKide® Plus (AMC) Specific Substrate for Anthrax Lethal Factor |
100nmoles |
4250 |
list539 |
Unquenched Calibration Peptide for MAPKKideÒ 530 |
50nmoles |
2890 |
list540 |
VAMPtide® Peptide Substrate (o-Abz/Dnp) |
200nmoles |
8500 |
list541 |
VAMPtide® Peptide Substrate (FITC/DABCYL) |
200nmoles |
8500 |
list542 |
VAMPtide® Peptide Substrate (PL 150, Pya/Nop) |
200nmoles |
8500 |
list549 |
Calibration Fluorophore for VAMPtideÒ 540 |
100nmoles |
2890 |
list550 |
SNAP Etide® Peptide Substrate (o-Abz/Dnp) |
100nmoles |
6800 |
list560 |
SYNTAXtideÒ Peptide Substrate (o-Abz/Dnp) for C. botulinum Type C |
200nmoles |
8500 |
list703 |
Anti-Cholera Toxin B Subunit (Goat) |
0.1ml |
3060 |
list752 |
Anti-Toxin A from Clostridium difficile (Goat) |
0.5ml |
3230 |
list760 |
Anti-Exotoxin A (Goat) |
0.5ml |
3400 |
list781 |
Anti-Protective Antigen from Bacillus anthracis (Goat) affinity purified, Liquid6,7 |
0.1mg |
7055 |
list100B |
Cholera Toxin (Azide Free)1 |
1mg |
3400 |
list101B |
Cholera Toxin1 |
1mg |
3400 |
list101C |
Cholera Toxin1 |
2mg |
5355 |
list116L |
Alpha Toxin from C. septicum4,6,7 |
50µg |
4930 |
list126A |
Epsilon Toxin from C. perfringens1,4,8 |
0.1mg |
5950 |
list128A |
Botulinum Neurotoxin Type A Complex from Clostridium botulinum1,3 |
10µg |
2890 |
list128C |
Botulinum Neurotoxin Type A Complex from Clostridium botulinum1,3 |
100µg |
5440 |
list130A |
Botulinum Neurotoxin Type A from Clostridium botulinum1,3 |
10µg |
5440 |
list130B |
Botulinum Neurotoxin Type A from Clostridium botulinum1,3 |
100µg |
13600 |
list133L |
Botulinum Neurotoxin Type A Toxoid, Liquid6,7 |
10µg |
5440 |
list136A |
Botulinum Neurotoxin Type B. from Clostridium botulinum 1,3 |
10µg |
5100 |
list136B |
Botulinum Neurotoxin Type B, from Clostridium botulinum1,3 |
100µg |
17000 |
list138A |
Botulinum Neurotoxin Type B Complex, Nicked, from Clostridium botulinum1,3 |
10µg |
2890 |
list138B |
Botulinum Neurotoxin Type B Complex, Nicked, from Clostridium botulinum1,3 |
100µg |
7225 |
list140A |
Botulinum Neurotoxin Type E, Nicked, Complex from Clostridium botulinum1,3 |
10µg |
2890 |
list140B |
Botulinum Neurotoxin Type E, Nicked, Complex from Clostridium botulinum1,3 |
100µg |
8925 |
list141A |
Botulinum Neurotoxin Type E, Nicked, from Clostridium botulinum1,3 |
10µg |
8075 |
list146A |
Botulinum Neurotoxin Type D, Nicked, Recombinant from Clostridium botulinum1,3 |
10µg |
5355 |
list149A |
Diphtheria Toxin CRM Mutant |
0.25 mg |
8500 |
list152C |
Toxin A from Clostridium difficile |
100µg |
9010 |
list154A |
Toxin B Toxoid from Clostridium difficile |
20µg |
2890 |
list15 |
Toxin B from Clostridium difficile |
2µg |
2890 |
list155B |
Toxin B from Clostridium difficile |
20µg |
8500 |
list155C |
Toxin B from Clostridium difficile |
200µg |
15300 |
list155L |
Toxin B from Clostridium difficile, Liquid6,7 |
50µg |
9860 |
list157A |
Binary Toxin from Clostridium difficile, A Subunit |
20µg |
5950 |
list158A |
Binary Toxin from Clostridium difficile, B Subunit |
40µg |
5950 |
list159A |
Glutamate Dehydrogenase (GDH) from Clostridium difficile6,7 |
0.1mg |
4930 |
list169A |
Anthrax Lethal Factor (LF-A) , Recombinant from Bacillus anthracis Native Sequence |
0.1mg |
3060 |
list169B |
Anthrax Lethal Factor (LF-A),Recombinant from Bacillus anthracis Native Sequence |
1mg |
12750 |
list169L |
Anthrax Lethal Factor (LF-A),Recomb.from Bacillus anthracis 5,7 |
0.2 mg |
5950 |
list171E |
Anthrax Protective Antigen (PA), Recombinant from Bacillus anthracis |
0.5mg |
8755 |
list172B |
Anthrax Lethal Factor (LF), Recombinant from Bacillus anthracis |
1mg |
12750 |
list172C |
Anthrax Lethal Factor (LF), Recombinant from Bacillus anthracis |
10mg |
39525 |
list172L |
Lethal Factor, Recomb from Bacillus anthracis, froz liq 5,7 |
1.0 mg |
12750 |
list173B |
Anthrax Edema Factor (EF), Recombinant Mutant S447N from Bacillus anthracis |
0.5mg |
16150 |
list176A |
Anthrax Lethal Factor (LF), Recombinant, Mutant E687C from Bacillus anthracis |
0.1mg |
5100 |
list176B |
Anthrax Lethal Factor (LF), Recombinant, Mutant E687C from Bacillus anthracis |
1mg |
16150 |
list177A |
Anthrax Protective Antigen Fragment (PA 20) from Bacillus anthracis |
50µg |
5950 |
list177B |
Anthrax Protective Antigen Fragment (PA 20) from Bacillus anthracis |
0.25mg |
11050 |
list178A |
Anthrax Edema Factor (EF), Recombinant from Bacillus anthracis |
0.1mg |
2890 |
list179A |
Pertussis Toxin Islet Activating Protein (in glycerol)6,7 |
50µg |
4845 |
list188L |
Adenylate Cyclase Toxin from B. pertussis, Recombinant, Frozen Liquid5,7 |
50µg |
5270 |
list190A |
Tetanus Toxin2 |
25µg |
2890 |
list190B |
Tetanus Toxin2 |
100µg |
9350 |
list191A |
Tetanus Toxoid |
25µg |
4675 |
list191B |
Tetanus Toxoid |
100µg |
13600 |
list196A |
C-fragment, FITC Conjugate |
10µg |
6800 |
list203A |
LPS, Escherichia coli O55:B5 |
2.5 mg |
3060 |
list500A |
SNAP-25 Recomb Protein Substrate for C. botulinum Type A and E Neurotoxin |
100µg |
5525 |
list510A |
GST Synaptobrevin-2 Protein Recomb. Protein Substrate for C. botulinum Type B,D and F |
100µg |
5950 |
list610A |
Botulinum Neurotoxin Type A Light Chain, Recombinant1 |
10µg |
4760 |
list611A |
Botulinum Neurotoxin Type A Light Chain, GST Fusion, Recombinant1 |
15µg |
4760 |
list612A |
Botulinum Neurotoxin Type A Heavy Chain, Recombinant, Binding Domain1 |
50µg |
4760 |
list613A |
Botulinum Neurotoxin Type A Heavy Chain, Recombinant, Binding Domain, GST Fusion1 |
50µg |
4760 |
list620A |
Botulinum Neurotoxin Type B Light Chain, Recombinant1 |
10µg |
8500 |
list622A |
Botulinum Neurotoxin Type B Heavy Chain, Recombinant, Binding Domain1 |
50µg |
4760 |
list623A |
Botulinum Neurotoxin Type B Heavy Chain, Recombinant, Binding Domain, GST Fusion1 |
50µg |
4760 |
list62 |
Botulinum Neurotoxin Type C Light Chain, Recombinant1 |
10µg |
8500 |
list630A |
Botulinum Neurotoxin Type D Light Chain, Recombinant1 |
10µg |
5695 |
list650A |
Tetanus Toxin Light Chain, Recombinant |
10µg |
3825 |
list690B |
Receptor for C. botulinum Type A Neurotoxin GST-SV2c luminal domain |
100nmoles |
6800 |
list730A |
Anti-Botulinum Neurotoxin, Type A (Chicken lgY), Liquid6,7 |
0.1mg |
5610 |
list731L |
Anti-Botulinum Neurotoxin, Type A (Mouse lgG monoclonal F1-40), Liquid6,7 |
0.1mg |
5950 |
list736A |
Anti-Botulinum Type B (Chicken lgY), Liquid6,7 |
0.1mg |
5950 |
list753A |
Anti-Clostridium difficile Toxin A (Chicken lgY), Liquid6,7 |
0.1mg |
5780 |
list754A |
Anti-Clostridium difficile Toxin B (Chicken lgY), Liquid6,7 |
0.1mg |
5780 |
list756A |
Anti-Clostridium difficile Glutamate Dehydrogenase, lgY, Liquid6,7 |
0.1mg |
5780 |
list757A |
Anti-Clostridium difficile Binary Toxin A subunit (Chicken lgY), Liquid6,7 |
0.1mg |
5780 |
list758A |
Anti-Clostridium difficile Binary Toxin B subunit (Chicken lgY), Liquid6,7 |
0.1mg |
5780 |
list759A |
Biotinylated Anti-Clostridium difficile Binary Toxin B subunit (Chicken lgY), Liquid6,7 |
0.1mg |
5780 |
list761L |
Anti-Shiga Toxin 1 (Rabbit), lgG, Liquid6,7 |
0.5mg |
3400 |
list765L |
Anti-Shiga Toxin 2 (Rabbit), IgG, Liquid6,7 |
0.5mg |
2890 |
list766L |
Anti-Shiga Toxin, Camelid Antibody, VHH, Liquid6,7 |
0.5mg/ml |
5950 |
list768L |
Biotinylated Anti-Lethal Factor from B. anthracis, IgY, Liquid6,7 |
0.1mg |
5950 |
list769B |
Anti-Lethal Factor from Bacillus anthracis (Chicken lgY), Liquid6,7 |
0.2mg |
8500 |
list771B |
Anti-Protective Antigen from Bacillus anthracis (Goat) |
1mg |
2890 |
list772B |
Anti-Lethal Factor from Bacillus anthracis (Goat) |
1.0 mg |
2890 |
list773L |
Anti-Edema Factor from Bacillus anthracis (Goat), Liquid6,7 |
1mg |
2890 |
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